COVID-19 natural immunity

Posted: 2021-08-09 More...

How does melanoma come into being?

Most moles are not dangerous, but melanoma may look like moles, and some may develop from moles. If ultraviolet radiation is excessive, usually through long-term exposure over a lifetime, melanocytes may begin to grow uncontrolled. If there is indeed excessive radiation, melanocytes will become melanoma, usually in people with a genetic predisposition to this condition.   Melanoma has the tendency to invade nearby tissues and then spread to the whole body through the blood or lymphatic system.

Posted: 2021-05-12 More...

Cutaneous lupus erythematosus? Effective medicine?

What is cutaneous lupus erythematosus?

Cutaneous lupus erythematosus is an immune disease that damages the skin and leads to the emergence of some antibodies. It mostly occurs in women of childbearing age, and may also occur in children and the elderly. Comprehensive factors such as heredity, infection, environment, sex hormones and drugs can lead to immune disorder and the occurrence of the disease. Most of the lesions of skin and mucous membrane can appear various rashes. The mild ones are slightly edematous erythema, and the severe ones can appear blisters, ulcers, erosion, skin atrophy and pigmentation. Butterfly erythema is a skin and mucous membrane manifestation with diagnostic specificity. Arthritis or joint swelling and pain, keratitis may also occur. Due to genetic and environmental factors, patients have lost immune tolerance, resulting in the production of antinuclear antibodies.

Posted: 2021-04-20 More...

How to deal cutaneous toxicities to EGFR inhibitors?

Recent studies have shown that the epidermal growth factor receptor (EGFR) plays a critical role in cancer development and progression, including cell proliferation, apoptosis, angiogenesis, and metastatic spread.
Posted: 2020-11-18 More...

Emerging roles of PPARS in inflammation and immunity

Peroxisome proliferator-activated receptors (PPARs) are members of the nuclear receptor family. After activation by specific ligands, they regulate the transcription of genes involved in lipid and lipoprotein metabolism, glucose and energy homeostasis,as well as cellular differentiation. Most studies have identified expression of the three PPARs in all cells of the arterial wall, where they control cholesterol homeostasis as well as the inflammatory response and, as a consequence, modulate atherogenesis. More generally, PPARs influence cell proliferation as well as the immune and inflammatory response in different tissues and cells.
Posted: 2020-10-28 More...

How to treat alopecia areata,Immunotherapy may be a good choice

Alopecia areata (AA) usually manifests as patches of non-scarring hair loss due to immune dysregulation.However, more severe forms may affect the entire scalp (alopecia totalis: AT) or body hair including eyebrows, cilia, axillary hair and hair of the pubis (alopecia universalis: AU).
Posted: 2020-04-28 More...

PPAR-β/δ plays a vital physiological role by regulating inflammation,cell proliferation, and differentiation

Peroxisome proliferator-activated receptor β/δ (PPAR-β/δ) is a ligand-activated transcription factor of the PPAR nuclear receptor family that plays important roles in the regulation of cellular metabolism by binding to sequence-specific DNA elements . PPAR-β/δ plays a vital physiological role by regulating inflammation, energy homeostasis, cell proliferation, and differentiation . Besides its expression in peripheral organs, PPAR-β/δ is also highly expressed in the central nervous system .
Posted: 2020-12-15 More...

Salmonella has become a serious threat,we need to access vaccines more effectiveness

Salmonella  is a Gram-negative facultative rod-shaped bacterium in the same proteobacterial family as Escherichia coli, the family Enterobacteriaceae, trivially known as "enteric" bacteria. Salmonella is nearly as well-studied as E. coli from a structural, biochemical and molecular point of view, and as poorly understood as E. coli from an ecological point of view. Salmonellae live in the intestinal tracts of warm and cold blooded animals. Some species are ubiquitous. Other species are specifically adapted to a particular host. In humans, Salmonella are the cause of two diseases called salmonellosis: enteric fever (typhoid), resulting from bacterial invasion of the bloodstream, and acute gastroenteritis, resulting from a foodborne infection/intoxication.At the beginning of the 19th century, typhoid was defined on the basis of clinical signs and symptoms and pathological (anatomical) changes. However, at this time, all sorts of enteric fevers were characterized as "typhoid".
Posted: 2020-09-01 More...

Citrus jabara can reduce allergic diseases and inflammationcan reduce allergic diseases and inflammation

Citrus jabara is a cultivar of citrus native to Kitayama village in Wakayama prefecture, Japan.Jabara has gained much attention in recent years for its effect on alleviating seasonal allergy symptoms . Jabara has been found to be particularly rich in the dietary flavonoid narirutin (naringenin-7-O-β-D-rutinoside) commonly found in citrus that is reported to possess anti-allergic property. The anti-allergic property of narirutin has been shown in both in vitro and in vivo studies using a mouse model of atopic dermatitis and airway inflammation.

Posted: 2020-04-20 More...

Volume 2, Issue 2, 2018 is now live!

The full issue of Volume 2, Issue 2, 2018 is now available online at here!
Posted: 2018-07-01

Volume 2, Issue 1, 2018 is now live!

The full issue of Volume 2, Issue 1, 2018 is now available online at here!
Posted: 2018-03-30

Volume 1, Issue 3, November 2017 is now live!

The full issue of Volume 1, Issue 3, November 2017 is now available online at here!
Posted: 2017-11-27

Trends in Immunotherapy Volume 1, Issue 2, August 2017 is now published online!

The full issue of Volume 1, Issue 2, August 2017 is now available online at here

Posted: 2017-08-29

The inaugural issue of Trends in Immunotherapy is now live!

We are pleased to announce that the inaugural issue of Trends in Immunotherapy (Volume 1, Issue 1, May 2017) has been officially published. The full issue is currently available for download at here.

Posted: 2017-05-29

Call for Papers

Enpress Publisher LLC. and the Chief Editor of Trends in Immunotherapy, Prof. Fukumi Furukawa, invite all authors to submit manuscripts for peer-review.

Posted: 2017-03-06 More...
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