Synthesis and in Vitro anticancer properties of Cu2–xSe–AIPH nanomaterials

Juan Lu, Yini Mao, Jun Yang

Article ID: 1408
Vol 5, Issue 1, 2022, Article identifier:10-18

VIEWS - 32 (Abstract) 22 (PDF)


The Cu2–xSe nanoparticles were synthesized by high temperature pyrolysis, modified with aminated polyethylene glycol in aqueous solution and loaded with compound 2,2′–azobis[2–(2–imidazolin–2–yl)propane] dihydrochloride (AIPH). The obtained nanomaterials can induce photothermal effect and use heat to promote the generation of toxic AIPH radicals under the irradiation of near-infrared laser (808 nm), which can effectively kill cancer cells. A series of in vitro experiments can preliminarily prove that Cu2–xSe–AIPH nanomaterials have strong photothermal conversion ability, good biocompatibility and anticancer properties.


Cu2–xSe Nanoparticles; AIPH; Photothermal Effect; Anticancer Properties

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