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Synthesis and in Vitro anticancer properties of Cu2–xSe–AIPH nanomaterials
Vol 5, Issue 1, 2022
VIEWS - 298 (Abstract) 240 (PDF)
Abstract
The Cu2–xSe nanoparticles were synthesized by high temperature pyrolysis, modified with aminated polyethylene glycol in aqueous solution and loaded with compound 2,2′–azobis[2–(2–imidazolin–2–yl)propane] dihydrochloride (AIPH). The obtained nanomaterials can induce photothermal effect and use heat to promote the generation of toxic AIPH radicals under the irradiation of near-infrared laser (808 nm), which can effectively kill cancer cells. A series of in vitro experiments can preliminarily prove that Cu2–xSe–AIPH nanomaterials have strong photothermal conversion ability, good biocompatibility and anticancer properties.
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DOI: https://doi.org/10.24294/can.v5i1.1408
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