Post-COVID-19 vaccination and the brain: A critical analysis of CNS MRI findings

Sadegh Ghaderi, Sana Mohammadi

Article ID: 2885
Vol 7, Issue 2, 2023

VIEWS - 518 (Abstract) 128 (PDF)

Abstract


The coronavirus disease 2019 (COVID-19) pandemic has led to an urgent need for vaccine development and global distribution. Recent research suggests that there may be potential impacts on the central nervous system (CNS), as evidenced by findings from magnetic resonance imaging (MRI). This article aims to provide feedback on the current evidence regarding the associations between COVID-19 vaccination and neurological complications. It is essential to conduct further research to enhance our scientific understanding of how vaccines interact with the central nervous system. This knowledge can significantly support public health efforts in controlling the spread of new viral variants through widespread vaccination.


Keywords


COVID-19; vaccination; central nervous system; magnetic resonance imaging; neurological complications

Full Text:

PDF


References


1. Chatterjee A, Chakravarty A. Neurological complications following COVID-19 vaccination. Current Neurology and Neuroscience Reports 2022; 23(1): 1–14. doi: 10.1007/s11910-022-01247-x

2. Ghaderi S, Mohammadi S, Heidari M, et al. Post-COVID-19 vaccination CNS magnetic resonance imaging findings: A systematic review. The Canadian Journal of Infectious Diseases & Medical Microbiology 2023; 2023: 1570830. doi: 10.1155/2023/1570830

3. Haque A, Pant AB. Mitigating Covid-19 in the face of emerging virus variants, breakthrough infections and vaccine hesitancy. Journal of Autoimmunity 2022; 127: 102792. doi: 10.1016/j.jaut.2021.102792

4. Rinaldi V, Bellucci G, Buscarinu MC, et al. CNS inflammatory demyelinating events after COVID-19 vaccines: A case series and systematic review. Frontiers in Neurology 2022; 13: 1018785. doi: 10.3389/fneur.2022.1018785

5. Tepmongkol S, Suwanwela NC, Hirankarn N, et al. Brain perfusion single photon emission computed tomography abnormality in MRI-negative stroke-like patients post COVID-19 vaccination. Medicine 2022; 101(47): e31965. doi: 10.1097/md.0000000000031965

6. Mirmosayyeb O, Bagherieh S, Shaygannejad V. Acute CNS demyelination in a subject with cerebellar ataxia following the first dose of COVID-19 vaccine; a case report. Human Vaccines & Immunotherapeutics 2021; 17(11): 4099–4101. doi: 10.1080/21645515.2021.1971920

7. Elnahry AG, Asal ZB, Shaikh N, et al. Optic neuropathy after COVID-19 vaccination: A report of two cases. International Journal of Neuroscience 2021; 133(8): 901–907. doi: 10.1080/00207454.2021.2015348




DOI: https://doi.org/10.24294/ti.v7.i2.2885

Refbacks

  • There are currently no refbacks.


Copyright (c) 2023 Sadegh Ghaderi, Sana Mohammadi

License URL: https://creativecommons.org/licenses/by-nc/4.0/

This site is licensed under a Creative Commons Attribution 4.0 International License.