A pediatric case of exudative erythema multiforme probably associated with asymptomatic COVID-19

Yoshihiro Wada, Kayoko Minami, Masaru Natsuaki, Nobuo Kanazawa

Article ID: 2397
Vol 7, Issue 2, 2023

VIEWS - 557 (Abstract)

Abstract


COVID-19 is a pandemic involving severe acute respiratory syndrome-coronavirus SARS-CoV-2, which started in China at the end of 2019 and has spread globally. Among COVID-19 patients, 17.8% are under 20 years of age. Most children infected with SARS-CoV-2 are asymptomatic or only oligosymptomatic and can easily be overlooked. We followed an 11-year-old boy showing exudative erythema multiforme, which appeared during isolation at home following a positive polymerase chain reaction (PCR) test for COVID-19. Our case, although otherwise asymptomatic, showed typical clinical and histological manifestations of the erythema multiforme-like lesions associated with COVID-19. The presence of such an asymptomatic SARS-CoV-2 carrier who developed erythema multiforme-like skin lesions provides the possibility that some undefined infectious organisms, such as SARS-CoV-2, could be the origin of exudative erythema multiforme cases without any apparent cause.


Keywords


COVID-19; severe acute respiratory syndrome-coronavirus-2; polymerase chain reaction; asymptomatic; exudative erythema multiforme

Full Text:

PDF


References


1. Wu Z, McGoogan JM. Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: Summary of a report of 72314 cases from the Chinese Center for Disease Control and Prevention. Journal of the American Medical Association 2020; 323(13): 1239–1242. doi: 10.1001/jama.2020.2648

2. Khalili M, Iranmanesh B, Mohammadi S, Aflatoonian M. Cutaneous and histopathological features of coronavirus disease 2019 in pediatrics: A review article. Dermatologic Therapy 2021; 34: e14554. doi: 10.1111/dth.14554

3. Hoang A, Chorath K, Moreira A, et al. COVID-19 in 7780 pediatric patients: A systematic review. eClinicalMedicine 2020; 24: 100433. doi: 10.1016/j.eclinm.2020.100433

4. Parri N, Lenge M, Buonsenso D. Children with Covid-19 in pediatric emergency departments in Italy. The New England Journal of Medicine 2020; 383(2): 187–190. doi: 10.1056/NEJMc2007617

5. Li H, Zhao Y, Zhou L. Cutaneous manifestations in children with SARS-CoV-2 infection and/or COVID-19: What do we know after 10 months under this pandemic? International Journal of Dermatology 2022; 61: 39–45. doi: 10.1111/ijd.15882

6. Wollina U, Karadağ AS, Rowland-Payne C, et al. Cutaneous signs in COVID-19 patients: A review. Dermatologic Therapy 2020; 33(5): e13549. doi: 10.1111/dth.13549

7. Torrelo A, Andina D, Santonja C, et al. Erythema multiforme-like lesions in children and COVID-19. Pediatric Dermatology 2020; 37(3): 442–446. doi: 10.1111/pde.14246




DOI: https://doi.org/10.24294/ti.v7.i2.2397

Refbacks

  • There are currently no refbacks.


Copyright (c) 2023 Yoshihiro Wada, Kayoko Minami, Masaru Natsuaki, Nobuo Kanazawa

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

This site is licensed under a Creative Commons Attribution 4.0 International License.