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Sinus histiocytosis with with massive lymphadenopathy is a benign lymphoproliferative disorder.In 1969, Rosai and Dorfman[1] made detailed research on it, so it was also called Rosai DorfnlRn disease (rosai.dorfmandisease, RDD).The clinical manifestations were fever, neck lymph node enlargement, leukocytosis and high gamma globulin.Histopathological findings showed that lymph node involvement was present in group RDD, and the infiltration of the cells was predominant, especially the phagocytosis of the histiocytic cells.About 43% of RDD patients have lymph node involvement in [2], in which the skin is the most common extranodal organs involved.About 10% of patients with skin damage, skin rash and morphological diversity, is easy to be misdiagnosed.In this paper, through the analysis of a case of RDD and EB virus infection, in clinical in patients with special infection can be early detection and treatment.
Objective: To improve the efficiency of cervical intervertebral discs hernia by determining the ultrasound biomarkers. Materials and Methods: The study included 38 healthy adolescents with normal intervertebral discs and neurologic status and 21 person with the disc hernia. Ultrasonography (USG) was performed at the level of disks C2-C3, C3-C4, C4-C5, C5-C6, C6-C7, C7-Тh1 in longitudinal and transverse projections. In axial section was performed the sagittal intervertebral disc and spinal canal sizes, the anterior dural space size, the width of spinal nerve canals. Results: In 9 (42,9±10,8% ) cases, the hernia was localized at the level of C5-C6, in 7 (33,3 ±10,3%) - C4-C5, in 2 (9,5±6,4%) - at the level of C2-C3 and C6-C7 C7, in 1 (4,8±4,7%) – at the level of C3-C4 respectively. In 13 (61,9±10,6%) cases the hernia had paramedian, in 5 (23,8±9,3%) cases – median, in 3 (14,3±7,6) cases – posterolateral localization. The paramedian hernia was significantly more frequently recorded than the posterolateral (P<0,05) and median hernia (p <0.001). Conclusions: In adolescents in the cervical spine, paramedian hernia are most commonly found, which are most often localized at the level of both C5-C6 and C4-C5. The greatest narrowing and deformation of the spinal nerve canal is observed by posterolateral and paramedian hernia, dural space – by median hernia respectively.