Background: Langerhans cell histiocytosis is a relatively rare unique disease process characterized by an abnormal proliferation of immature dendritic cells usually affecting children and young adults.

Discussion:  Histiocytosis are rare diseases of great biological variability and a wide range of clinical manifestations. The first manifestations of LCH may occur in the oral cavity may vary from a continuous gingival infection or a dental abscess to necrotizing ulcerating defects or a painful jaw swelling.The criteria  for diagnosis of LCH includes identification of the characteristic clinical features histopathological, Immunohistochemical findings. Various treatment modalities has been adopted including wide surgical excision along with radiotherapy,chemotherapy ,isolated radiotherapy and use of alkalizing agents.

The liver is the second largest human organ and has got a complex internal vascular and ductal anatomy. It is subdivided into lobes, sections and segments and receives dual blood supply from the hepatic artery and portal vein. The hepatic veins drain the liver directly into the inferior vena to which the liver is intimately related. Anatomical variations are common. A thorough knowledge of the liver anatomy and its variations is of critical importance for safe and successful procedures and surgeries involving the liver.