Synthesis and characterization methods of polymeric nanoparticles

Aslı Katmıs; Serap Fide; Seyma Karaismailoglu; Serap Derman

doi:10.24294/can.v2i2.791

Synthesis and characterization methods of polymeric nanoparticles

Aslı Katmıs, Serap Fide, Seyma Karaismailoglu, Serap Derman

Article ID: 791
Vol 2, Issue 2, 2019

VIEWS - 5524 (Abstract) 2905 (PDF)

Abstract

This review provided a detailed overview of the different synthesis and characterization methods of polymeric nanoparticles. Nanoparticles are defined as solid and colloidal particles of macromolecular substances ranging in size under 100 nm. Different types of nanoparticles are used in many biological fields (bio-sensing, biological separation, molecular imaging, anticancer therapy, etc.). The new features and functions provided by nano dimensions are largely different from their bulk forms. High volume/surface ratio, improved resolution and multifunctional capability make these materials gain many new features.

Keywords

Nanoparticle; Polymer; Synthesis Methods; Characterization Methods; Particle Size

Full Text:

PDF

References

1. Singh R, Lillard Jr JW. Nanoparticle-based targeted drug delivery. Experimental and Molecular Pathology 2009; 86(3): 215–223.

2. Khan I, Saeed K, Khan I. Nanoparticles: Properties, applications and toxicities. Arabian Journal of Chemistry 2017; 12(7): 908–931.

3. Dash TK, Konkimalla VB. Poly-caprolactone based formulations for drug delivery and tissue engineering: A review. Journal of Controlled Release Society 2012; 158(1): 15–33.

4. Szot CS, Buchanan CF, Gatenholm P, et al. Investigation of cancer cell behavior on nanofibrous scaffolds. Materials Science and Engineering: C 2011; 31(1): 37–42.

5. Hughes GA. Nanostructure-mediated drug delivery. Nanomedicine Nanotechnology Biology & Medicine, 2005, 1(1): 22–30.

6. Faraji AH, Wipf P. Nanoparticles in cellular drug delivery. Bioorganic & medicinal chemistry 2009; 17(8): 2950–2962.

7. Mansour HM, Sohn MJ, Al-Ghananeem A, et al. Materials for pharmaceutical dosage forms: Molecular pharmaceutics and controlled release drug delivery aspects. International journal of molecular sciences 2010; 11(9): 3298–3322.

8. Parveen S, Misra R, Sahoo SK. Nanoparticles: A boon to drug delivery, therapeutics, diagnostics and imaging. Nanomedicine: Nanotechnology, Biology and Medicine 2012; 8(2): 147–166.

9. Mohanraj V, Chen Y. Nanoparticles: A review. Tropical Journal of Pharmaceutical Research 2006; 5(1): 561–573.

10. Langer R. Biomaterials in drug delivery and tissue engineering: one laboratory’s experience. Accounts of Chemical Research 2000; 33(2): 94–101.

11. Lee M, Kim SW. Polyethylene glycol-conjugated copolymers for plasmid DNA delivery. Pharmaceutical Research 2005; 22(1): 1–10.

12. Esfanjani AF, Jafari SM. Biopolymer nano-particles and natural nano-carriers for nano-encapsulation of phenolic compounds. Colloids and Surfaces B: Biointerfaces 2016; 146: 532–543.

13. Kashi T, Eskandarion S, Esfandyari-Manesh M, et al. Improved drug loading and antibacterial activity of minocycline-loaded PLGA nanoparticles prepared by solid/oil/water ion pairing method. International Journal of Nanomedicine 2012; 7: 221–234.

14. Derman S, Kizilbey K, Akadeste ZM. Polymeric nanoparticles. Sigma 2013; 31: 107–120.

15. Öztürk K. Design and evaluation of nanoparticle carrier systems containing free radical cleaner material [Master’s thesis] (in Turkish). Ankara: Hacettepe University; 2010.

16. Quintanar-Guerrero D, Allémann E, Fessi H et al. Preparation techniques and mechanisms of formation of biodegradable nanoparticles from preformed polymers. Drug Development and Industrial Pharmacy 1998; 24(12): 1113–1128.

17. Rao JP, Geckeler KE. Polymer nanoparticles: Preparation techniques and size-control parameters. Pro- gress in Polymer Science 2011; 36(7): 887–913.

18. Reis CP, Neufeld RJ, Ribeiro AJ, et al. Nanoencapsulation I. Methods for preparation of drug-loaded polymeric nanoparticles. Nanomedicine: Nanotechnology, Biology and Medicine 2006; 2(1): 8–21.

19. Nagavarma B, Hemant KSY, Ayaz A, et al. Different techniques for preparation of polymeric nanoparticles — A review. Asian Journal of Pharmaceutical and Clinic Research 2012; 5(3): 16–23.

20. Fonseca AC, Ferreira P, Cordeiro RA et al. Drug delivery systems for predictive medicine: polymers as tools for advanced applications. In: New strategies to advance pre/diabetes care: Integrative approach by PPPM. Springer; 2013. p. 399–455.

21. Mishra B, Patel BB, Tiwari S. Colloidal nanocarriers: A review on formulation technology, types and applications toward targeted drug delivery. Nanomedicine: Nanotechnology, Biology and Medicine 2010; 6(1): 9–24.

22. Bilati U, Allémann E, Doelker E. Development of a nanoprecipitation method intended for the entrapment of hydrophilic drugs into nanoparticles. European Journal of Pharmaceutical Sciences 2005; 24 (1): 67–75.

23. Klippstein R, Wang JTW, Riham I, et al. Passively targeted curcumin-loaded PEGylated PLGA nanoca-psules for colon cancer therapy in vivo. Small 2015; 11(36): 4704–4722.

24. Sun Y, Mohammed J. Meziani, et al. Polymeric nanoparticles from rapid expansion of supercritical fluid solution. Chemistry-A European Journal 2005; 11(5): 1366–1373.

25. Thote AJ, Gupta RB. Formation of nanoparticles of a hydrophilic drug using supercritical carbon dioxide and microencapsulation for sustained release. Nanomedicine: Nanotechnology, Biology and Medicine 2005; 1(1): 85–90.

26. Özcan İ. Design and evaluation of in vitro-in vivo nanoparticle drug-ing systems prepared using biodegradable polymers synthesized to target bone [Master’s thesis] (In Turkish). Izmir: Ege University; 2008.

27. Molpeceres J, Aberturas M, Guzman M. Biodegrad-able nanoparticles as a delivery system for cyclosporine: Preparation and characterization. Journal of Microencapsulation 2000; 17(5): 599–614.

28. Zhou W, Wang Z. Scanning microscopy for nanotechnology: Techniques and applications. Springer; 2007.

29. Şimsek UB. Zero value iron nanoparticle production, optimization and use of textile dyeing under different synthesis conditions [Master’s thesis] (In Turkish). Mersin: Mersin University; 2015. p. 131.

30. Tokay B, Erdem Şenatalar A. Investigation of the mechanism of silicate-1 synthesis from nanotanes (in Turkish). ITU Dergisi D 2011; 7(5).

31. Li H. Atomic force microscopy [Internet]. 1997 [updated 1997 April 24] Available from: http://www.Cheimstry.uoguelph.ca/educmat/chm729/afm/firstpag.htm

32. Cohen SH, Bray MT, Lightbody ML. Atomic force microscopy/scanning tunneling microscopy. Plenum Press; 2002.

33. Karaağaç Ö. Synthesis, characterization and enzyme immobilization application of superparamagnetic nanoparticles with optimum saturation magnetization [Master’s thesis] (in Turkish). Balikesir: Balikesir University; 2007-2011.

34. Cullity BD, Stock SR. Elements of X-ray diffraction. New York: Prentice-Hall; 2001.

35. Skoog DA, Holler FJ, Nieman TA. Principles of instrumental analysis. Toronto: Thomson Learning. Inc.; 1998.

36. Bootz A, Vogel V, Schubert D, et al. Comparison of scanning electron microscopy, dynamic light scattering and analytical ultracentrifugation for the sizing of poly (butyl cyanoacrylate) nanoparticles. European Journal of Pharmaceutics and Biopharmaceutics 2004; 57(2): 369–375.

37. Xu R. Progress in nanoparticles characterization: Sizing and zeta potential measurement. Particuology 2008; 6(2): 112–115.

38. Clogston JD, Patri AK. Zeta potential measurement. In: Characterization of nanoparticles intended for drug delivery. Springer; 2011.p. 63–70.

DOI: https://doi.org/10.24294/can.v2i2.791