Bacterial nanocellulose-Robust preparation and application—A literature review

Anbazhagan Thirumalai, Agnishwar Girigoswami, Koyeli Girigoswami

Article ID: 2170
Vol 6, Issue 3, 2023

VIEWS - 698 (Abstract) 111 (PDF)


Increasing attention is being paid to bacterial nanocellulose (BNC) because of its environment-friendly properties. Researchers investigated the role of microbial hosts in BNC production due to the benefits of cellulose produced by microbes. Several research groups have developed techniques to make BNC on a large scale with the goal of developing new methods. A 3D network of micro and nanofibrils in BNC synthesized from several bacterial strains makes these BNC useful for reinforcing nanostructured composites that have increased Young’s modulus, tensile strength, purity, crystallinity, and water holding capacity. To overcome the barriers associated with the industrial scale production of BNC, different production techniques will be used, including static culture, cell-free production, agitated/shaking culture, using a variety of receptors for fermentation, and low-cost substrates as carbon sources. By in-situ and ex-situ fermentation processes, metal/metal oxide nanoparticle composites are among the most widely used materials in diagnostic and regenerative medicine. The purpose of the review is to update the researchers regarding the lucid production process and versatile applications of bacterial nanocellulose in biomedical field. We shall mainly discuss about the different methods for bacterial cellulose production and some of its applications in this mini-review.


bacterial nanocellulose; production of BNC; biomedical applications; tissue engineering; biosensing

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