Antiviral and anti-inflammatory effects of medicated thread moxibustion combined with Shujin Jiannao granule in the treatment of HFMD

Abstract

Objective To investigate antiviral and anti-inflammatory effects of medicated thread moxibustion combined with Shujin Jiannao granule in the treatment of HFMD. Methods A total of 124 children with HFMD were collected to divided into western medicine group (62 cases) and experimental group(62 cases) while 62 healthy children were enrolled to become normal control group. Western medicine group was treated according to conventional therapy while experimental group was treated with combined treatment of traditional Chinese medicine(TCM) and western medicine. To determine serum levels of S100B, NSE, CRP and WBC and observe the clinical effectiveness. Results In the western medicine group the total effectiveness rate is 88.7% while it is 96.8% in the experimental group（P<0.05）; the average disappearance time of symptoms are shorter in the experimental group than that in the western medicine group（P<0.05）. Compared with the control group，the serum levels of S100B, NSE, CRP and WBC all rise in HFMD children（P<0.05 or P<0.01）. After treatment , the serum levels of S100B, NSE, CRP and WBC reduce in both the experimental group and the western medicine group, when compared with that before treatment.The difference is statistically significant（P<0.05 or P<0.01）.