This comprehensive investigation and meta-analysis explored the effectiveness and safety of stereotactic radiotherapy and microsurgery in treating vestibular schwannomas. A thorough review of pertinent studies published from 2004 to 2023 was undertaken, examining the outcomes of both Gamma Knife radiosurgery and linear accelerator-based stereotactic irradiation. The primary focus was on assessing tumor control rates, hearing preservation, quality of life, and the long-term impact of treatment. The results suggest that stereotactic radiotherapy holds considerable promise as a well-tolerated treatment option for managing vestibular schwannomas. It demonstrates favorable tumor control rates, the potential to preserve hearing, and a positive influence on patients’ overall well-being. However, the study also emphasizes the importance of vigilant monitoring and assessment due to the challenges associated with tumor pseudo-progression. Further investigation and prospective studies are necessary to refine treatment protocols and validate the presented conclusions.

vestibular schwannoma; neurosurgery; stereotactic radiotherapy; brain tumor

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