Exaggeration of consequences of low-dose radiation exposures with special reference to cataracts

Sergei V. Jargin

Article ID: 3387
Vol 6, Issue 1, 2023

VIEWS - 70 (Abstract) 25 (PDF)

Abstract


Publications overestimating the medical and ecological sequels of a slight anthropogenic increase in the radiation background have been reviewed recently with examples of different organs and pathological conditions. The overestimation contributed to the strangulation of atomic energy. The use of nuclear energy for electricity production is on the agenda today due to the increasing energy needs of humankind. Apparently, certain scientific writers acted in the interests of fossil fuel producers. Health risks and environmental damage are maximal for coal and oil, lower for natural gas, and much lower for atomic energy. This letter is an addition to previously published materials, this time focused on studies of cataracts in radiation-exposed populations in Russia. Selection and self-selection bias are of particular significance. Apparently, the self-reporting rate correlates with dose estimates and/or with professional awareness about radiation-related risks among nuclear workers or radiologic technologists, the latter being associated with their work experience/duration and hence with the accumulated dose. Individuals informed of their higher doses would more often seek medical advice and receive more attention from medics. As a result, lens opacities are diagnosed in exposed people earlier than in the general population. This explains dose-effect correlations proven for the incidence of cataracts but not for the frequency of cataract surgeries. Along the same lines, various pathological conditions are more often detected in exposed people. Ideological bias and the trimming of statistics have not been unusual in the Russian medical sciences. It is known that ionizing radiation causes cataracts; however, threshold levels associated with risks are understudied. In particular, thresholds for chronic and fractionated exposures are uncertain and may be underestimated.


Keywords


ionizing radiation; cataract; lens opacity; East Urals radioactive trace

Full Text:

PDF


References


1. Paehlke RC. Environmentalism and the Future of Progressive Politics. Yale University Press; 1989. doi: 10.2307/j.ctt1ww3v5w

2. Jargin S. Overestimation of Cardiovascular Consequences of Low Dose Radiation Exposures. Cambridge Scholars Publishing; 2023.

3. Jargin SV. The overestimation of medical consequences of low-dose exposures: Cui bono? Environmental Disease 2021; 6(3): 101–107. doi: 10.4103/ed.ed_13_21

4. Jaworowski Z. Observations on the Chernobyl disaster and LNT. Dose-Response 2010; 8(2). doi: 10.2203/dose-response.09-029.jaworowski

5. Schreurs M, Papadakis E. Historical Dictionary of the Green Movement. Rowman & Littlefield; 2020.

6. Drake BA, Cronon W. Loving Nature, Fearing the State: Environmentalism and Antigovernment Politics before Reagan. University of Washington Press; 2013.

7. Garcia-Johnson R. Exporting Environmentalism. The MIT Press; 2000. doi: 10.7551/mitpress/2941.001.0001

8. OECD. Trends towards Sustainability in the Nuclear Fuel Cycle. OECD; 2011. doi: 10.1787/9789264168268-en

9. Llewellyn Smith C, Ward D. The path to fusion power. Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences 2007; 365(1853): 945–956. doi: 10.1098/rsta.2006.1956

10. Duffy DM. Fusion power: A challenge for materials science. Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences 2010; 368(1923): 3315–3328. doi: 10.1098/rsta.2010.0060

11. Jargin SV. Overestimation of medical consequences of low-dose radiation exposures and overtreatment of cancer. Journal of Health Science Research 2023. doi: 10.25259/JHSR_36_2023

12. Azizova TV, Grigoryeva ES, Haylock RGE, et al. Ischaemic heart disease incidence and mortality in an extended cohort of Mayak workers first employed in 1948–1982. The British Journal of Radiology 2015; 88(1054): 20150169. doi: 10.1259/bjr.20150169

13. Moseeva MB, Azizova TV, Grigoryeva ES, et al. Risks of circulatory diseases among Mayak PA workers with radiation doses estimated using the improved Mayak Worker Dosimetry System 2008. Radiation and Environmental Biophysics 2014; 53(2): 469–477. doi: 10.1007/s00411-014-0517-x

14. Ivanov VK, Maksioutov MA, Chekin SYu, et al. The risk of radiation-induced cerebrovascular disease in chernobyl emergency workers. Health Physics 2006; 90(3): 199–207. doi: 10.1097/01.hp.0000175835.31663.ea

15. Kashcheev VV, Chekin SYu, Maksioutov MA, et al. Radiation-epidemiological study of cerebrovascular diseases in the cohort of Russian recovery operation workers of the chernobyl accident. Health Physics 2016; 111(2): 192–197. doi: 10.1097/hp.0000000000000523

16. Little MP. Radiation and circulatory disease. Mutation Research/Reviews in Mutation Research 2016; 770: 299–318. doi: 10.1016/j.mrrev.2016.07.008

17. Azizova TV, Bragin EV, Hamada N, et al. Risk of cataract incidence in a cohort of Mayak PA workers following chronic occupational radiation exposure. PLOS ONE 2016; 11(10): e0164357. doi: 10.1371/journal.pone.0164357

18. Азизова Т, Azizova T, Брагин Е, et al. Risk assessment of senile cataract incidence in a cohort of nuclear workers of Mayak production association. Medical Radiology and Radiation Safety 2018; 63: 15–21. doi: 10.12737/article_5b83b0430902e8.35861647

19. Bragin EV, Azizova TV, Bannikova MV. Risk of senile cataract among nuclear industry workers. Vestnik oftal’mologii 2017; 133(2): 57. doi: 10.17116/oftalma2017133257-63

20. Туков А, Tukov A, Каширина О, et al. To the article of T.V. Azizova, E.V. Bragin, N. Hamada, M.V. Bannikova “Risk Assessment of Senile Cataract Incidence in a Cohort of Nuclear Workers of Mayak Production Association”. Medical Radiology and Radiation Safety 2018; 63(6): 82–83. doi: 10.12737/article_5c0b8b4bcd76d1.44560283

21. Соловьев В, Solov’ev V, Краснюк В, et al. On possible mistakes in the estimation of radiation risk non-cancer effects in Mayak plant workers. Medical Radiology and Radiation Safety 2018; 63(6): 83–84. doi: 10.12737/article_5c0bdefea14005.22956834

22. Azizova TV, Hamada N, Grigoryeva ES, et al. Risk of various types of cataracts in a cohort of Mayak workers following chronic occupational exposure to ionizing radiation. European Journal of Epidemiology 2018; 33(12): 1193–1204. doi: 10.1007/s10654-018-0450-4

23. Worgul BV, Kundiyev YI, Sergiyenko NM, et al. Cataracts among Chernobyl clean-up workers: Implications regarding permissible eye exposures. Radiation Research 2007; 167(2): 233–243. doi: 10.1667/rr0298.1

24. Jargin SV. Solid cancer increase among Chernobyl liquidators: Alternative explanation. Radiation and Environmental Biophysics 2015; 54(3): 373–375. doi: 10.1007/s00411-015-0610-9

25. Rybkina VL, Azizova TV. The influence of the ionizing radiation on the development of atherosclerosis. Radiatsionnaia Biologiia, Radioecologiia 2016; 56(1): 44–55.

26. Azizova TV, Moseeva MB, Grigor'eva ES, et al. Mortality risk of cardiovascular diseases for occupationally exposed workers. Radiatsionnaia Biologiia, Radioecologiia 2012; 52(2): 158–166.

27. Azizova TV, Haylock RGE, Moseeva MB, et al. Cerebrovascular diseases incidence and mortality in an extended Mayak worker cohort 1948–1982. Radiation Research 2014; 182(5): 529. doi: 10.1667/rr13680.1

28. Azizova TV, Bannikova MV, Grigorieva ES, et al. Risk of lower extremity arterial disease in a cohort of workers occupationally exposed to ionizing radiation over a prolonged period. Radiation and Environmental Biophysics 2016; 55(2): 147–159. doi: 10.1007/s00411-016-0645-6

29. Azizova TV, Muirhead CR, Moseeva MB, et al. Cerebrovascular diseases in nuclear workers first employed at the Mayak PA in 1948–1972. Radiation and Environmental Biophysics 2011; 50(4): 539–552. doi: 10.1007/s00411-011-0377-6

30. Moseeva MB, Azizova TV, Muirhed CR, et al. Risk of cerebrovascular disease incidence in the cohort of Mayak production association workers first employed during 1948–1958. Radiatsionnaia Biologiia, Radioecologiia 2012; 52(2): 149–157.

31. Azizova TV, Hamada N, Bragin EV, et al. Risk of cataract removal surgery in Mayak PA workers occupationally exposed to ionizing radiation over prolonged periods. Radiation and Environmental Biophysics 2019; 58(2): 139–149. doi: 10.1007/s00411-019-00787-0

32. Little MP, Cahoon EK, Kitahara CM, et al. Occupational radiation exposure and excess additive risk of cataract incidence in a cohort of US radiologic technologists. Occupational and Environmental Medicine 2019; 77(1): 1–8. doi: 10.1136/oemed-2019-105902

33. Ainsbury EA, Dalke C, Hamada N, et al. Radiation-induced lens opacities: Epidemiological, clinical and experimental evidence, methodological issues, research gaps and strategy. Environment International 2021; 146: 106213. doi: 10.1016/j.envint.2020.106213

34. Ainsbury EA, Barnard S, Bright S, et al. Ionizing radiation induced cataracts: Recent biological and mechanistic developments and perspectives for future research. Mutation Research/Reviews in Mutation Research 2016; 770: 238–261. doi: 10.1016/j.mrrev.2016.07.010

35. UNSCEAR. UNSCEAR 1982 Report. Annex J. Non-Stochastic Effects of Irradiation. UNSCEAR; 1982.

36. Stewart FA, Akleyev AV, Hauer-Jensen M, et al. ICRP publication 118: ICRP statement on tissue reactions and early and late effects of radiation in normal tissues and organs—Threshold doses for tissue reactions in a radiation protection context. Annals of the ICRP 2012; 41(1–2): 1–322. doi: 10.1016/j.icrp.2012.02.001

37. Hamada N, Azizova TV, Little MP. An update on effects of ionizing radiation exposure on the eye. The British Journal of Radiology 2020; 93(1115): 20190829. doi: 10.1259/bjr.20190829

38. Nakashima E, Neriishi K, Minamoto A. A reanalysis of atomic-bomb cataract data, 2000–2002: A threshold analysis. Health Physics 2006; 90(2): 154–160. doi: 10.1097/01.hp.0000175442.03596.63

39. Mikryukova LD, Akleyev AV. Cataract in the chronically exposed residents of the Techa riverside villages. Radiation and Environmental Biophysics 2017; 56(4): 329–335. doi: 10.1007/s00411-017-0702-9

40. Barnard SGR, Hamada N. Individual response of the ocular lens to ionizing radiation. International Journal of Radiation Biology 2022; 99(2): 138–154. doi: 10.1080/09553002.2022.2074166

41. List of countries by life expectancy. Available online: https://en.wikipedia.org/wiki/List_of_countries_by_life_expectancy (accessed on 18 January 2024).

42. Chuchalin AG, Maracheva AV, Grobova OM, et al. Lungs exposed to nuclear catastrophe: One-year therapeutic programme in Chernobyl liquidators group. Schweizerische Medizinische Wochenschrift 1997; 127(5): 165–169.

43. Kogan EA, Cherniaev AL, Chuchalin AG, et al. Morphologic and molecular-genetic characterization of lung cancer developing in people who have worked at nuclear facilities and who have lived in Russian territories polluted after the accident at the Chernobyl power plant. Arkhiv Patologii 1999; 61(1): 22–26.

44. Lysenko AI, Kirpatovskiĭ ID, Pisarenko SS. Morphological changes in male sexual glands in Kaluga regions contaminated with radionuclides. Arkhiv Patologii 2000; 62(4): 27–31.

45. Jargin SV. Overestimation of cardiovascular consequences of low dose low rate ionizing radiation. Life Sciences: An International Journal (LSIJ) 2023; 1(1): 51–59.

46. Jargin SV. Thyroid cancer after Chernobyl: Obfuscated truth. Dose-Response 2011; 9(4). doi: 10.2203/dose-response.11-001.jargin

47. Jargin SV. Overestimation of medical consequences of nuclear testing in Semipalatinsk area: An example. Available online: https://www.bmj.com/rapid-response/2011/11/02/overestimation-medical-consequences-nuclear-testing-semipalatinsk-area-exa (accessed on 18 January 2024).

48. Okladnikova ND, Sumina MV, Pesternikova VS, et al. Long-term consequences of external gamma-radiation according to the results of the observation of the personnel of the first atomic power plant in the country. Klinicheskaia Meditsina 2007; 85(10): 21–26.

49. Gus’kova AK. Fifty years of the nuclear industry in Russia—Through the eyes of a physician. Atomic Energy 1999; 87(6): 903–908. doi: 10.1007/bf02673545

50. Yarmonenko SP, Wainson AA. Radiobiology of Humans and Animals. Visshaya Shkola; 2004.

51. Moskalev YuI. Long-term Effects of Exposure to Ionizing Radiation. Medicina; 1991.

52. Buldakov LA, Demin SN, Kostyuchenko VA, et al. Medical consequences of the radiation accident in the Southern Urals in 1957. Medical Radiology 1990; 35(12): 11–16.

53. Kostyuchenko VA, Krestinina LY. Long-term irradiation effects in the population evacuated from the East-Urals radioactive trace area. Science of The Total Environment 1994; 142(1–2): 119–125. doi: 10.1016/0048-9697(94)90080-9

54. Okladnikova ND, Pesternikova VS, Azizova TV, et al. Health status among the staff at the nuclear waste processing plant. Meditsina Truda i Promyshlennaia Ekologiia 2000; 6: 10–14.

55. Akleyev AV, Kossenko MM, Krestinina LYu, et al. Health Status of Population Exposed to Environmental Contamination in the Southern Urals. Radekon; 2001.

56. Akleev AV, Preston D, LIu K. Medical and biological consequences of human’s chronic exposure to radiation. Meditsina Truda i Promyshlennaia Ekologiia 2004; (3): 30–36.

57. Rühm W, Breckow J, Dietze G, et al. Dose limits for occupational exposure to ionising radiation and genotoxic carcinogens: A German perspective. Radiation and Environmental Biophysics 2019; 59(1): 9–27. doi: 10.1007/s00411-019-00817-x

58. McCarron RA, Barnard SGR, Babini G, et al. Radiation-induced lens opacity and cataractogenesis: A lifetime study using mice of varying genetic backgrounds. Radiation Research 2021; 197(1). doi: 10.1667/rade-20-00266.1

59. Worgul BV, Smilenov L, Brenner DJ, et al. Mice heterozygous for the ATM gene are more sensitive to both X-ray and heavy ion exposure than are wildtypes. Advances in Space Research 2005; 35(2): 254–259. doi: 10.1016/j.asr.2005.01.030

60. Kleiman NJ. Radiation cataract. Annals of the ICRP 2012; 41(3–4): 80–97. doi: 10.1016/j.icrp.2012.06.018

61. Dalke C, Neff F, Bains SK, et al. Lifetime study in mice after acute low-dose ionizing radiation: A multifactorial study with special focus on cataract risk. Radiation and Environmental Biophysics 2018; 57(2): 99–113. doi: 10.1007/s00411-017-0728-z

62. Iavicoli I, Fontana L, Santocono C, et al. The challenges of defining hormesis in epidemiological studies: The case of radiation hormesis. Science of The Total Environment 2023; 902: 166030. doi: 10.1016/j.scitotenv.2023.166030

63. Doss M. Future of radiation protection regulations. Health Physics 2016; 110(3): 274–275. doi: 10.1097/hp.0000000000000381

64. Jargin SV. Misconduct in Medical Research and Practice. Nova Science Publishers Inc; 2020. doi: 10.52305/giez3244




DOI: https://doi.org/10.24294/irr.v6i1.3387

Refbacks

  • There are currently no refbacks.


Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Creative Commons License

This site is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.