Dear colleagues,

It is essential to monitor the neurodegenerative process early and accurately for various reasons, such as optimizing clinical management, providing opportunities for prevention, and increasing predictive accuracy. Neurodegenerative diseases have a significant impact on a large number of people globally. Advanced magnetic resonance neuroimaging is a rapidly evolving field that offers new insights into the brain and its disorders. Diseases such as Alzheimer's disease, Parkinson's disease, and motor neuron diseases are characterized by the progressive loss of neurons and synapses, resulting in motor, non-motor, and cognitive decline. The use of multi-technique and multiparametric MRI can enhance the specificity and sensitivity in diagnosing and monitoring neurodegenerative diseases. Imaging features range from conventional MRI sequences to advanced multiparametric methods such as volumetric structural MRI, resting-state and task-based functional MRI, diffusion tensor imaging tractography, and

arterial spin labeling imaging.

This section will encompass a wide range of topics, including (but not limited to) the following:

- The significance of advanced MRI in monitoring the neurodegenerative process

- New biomarkers for early detection and diagnosis of neurodegenerative diseases

- Inflammatory biomarkers as predictors of the progression of neurodegenerative diseases

- Challenges and opportunities in advanced neuroimaging biomarker research for clinical practice.

Neurodegeneration, Alzheimer's disease, Parkinson's disease, motor neuron disease, amyotrophic lateral sclerosis, MRI, fMRI, DTI, MRS, ASL, MRI biomarkers, multimodal imaging, machine learning, artificial inteligence