Spatial Distribution and Growth Period of Effective Components in Leaves of Taxus cuspidata

Megfei Tong, Mingsong Pan, Junfeng Li, Hua Ling

Article ID: 381
Vol 1, Issue 1, 2018

VIEWS - 544 (Abstract) 72 (PDF)

Abstract


Taxus cuspidata Sieb. ET. Zucc. is a taxus of Taxaceae, a rare third-order relict species distributed in northeastern China, and a wild endangered plant species protected by national level I. Taxol (paclitaxel, trade name taxol) and cephalomannine (cephalomannine) are all diterpenoids contained in the genus Taxus, with broad-spectrum anti-tumor activity and unique anti-cancer mechanism. In this study, the distribution of paclitaxel and cephalomannine in the leaves of Taxus cuspidata in different parts and different growth stages was discussed. The results showed that the content of two substances in the leaves of the majority of the crowns was lower than that of the biennial and tertiary there were no significant differences in the contents of two substances in the two-year and three-year-old

 

foliage. There was no significant difference in the contents of the two layers in the three levels of the noodles, and

 

the content of the male was slightly higher than that of the dark. The content of paclitaxel in the leaves of natural

 

northeast yew was the highest at dormancy period, and the content of flowering and fruit was not much different. The

 

content of Cephalotaxin was the highest in dormancy period, and that of cephalosporin the content of paclitaxel and

 

cephalomannine in each plant were significantly different. There was significant difference between the two plants.


Full Text:

PDF


References


1. Xu Liyan, Ji Mingshan. The role of plants in the plant itself. China Rural well-off technology, 2006,9: 52-54.

2. Dong Yanling, Pan Xuewu. Brief introduction of plant secondary metabolites. Biology Bulletin, 2002,37 (11): 17-19.

3. Yan Xiufeng. Plant secondary metabolic ecology. Chinese Journal of Plant Ecology, 2001,25 (5): 639-640.

4. Zhou Guifei, Xu Maojun. Biosynthesis of secondary metabolites of plants. Biology Bulletin, 2005,40 (12): 12-14.

5. Bai Guangxin, Wu Banghua, Zhang Qichang, et al. Research on Taxus chinensis in Northeast China. Beijing: China Forestry Press, 2002.

6. Li Yanhong. Taxi development and utilization of the current situation of China's high-tech enterprises, 2007 (4): 108-110.

7. Gao Ya Xian, Tong Lijun. Extreme development value of the Northeast Taxus. China Forest Deputy specialty, 1995: 54.

8. Chen Qinghong, Chen Qingying, Huang Liya, et al. Research progress of Taxus mairei development. China Wild Plant Resources, 2005,24 (1): 14,24.

9.

10. Spatial Distribution and Growth Period of Effective Components in Leaves of Taxus cuspidata

11. Chexi Zhe, Zhao Chuanyan, Zhao Haitao. Development Prospect and Benefit Analysis of Taxus cuspidata. Special Economic

12. Animal and Plant, 2004,5: 62,72.

13. Zhang Zhimin, Zhang Zhiguang, Pan Kefu. Northeast yew and its cultivation techniques. Forest teaching, 2008,7: 176-177.

14. Fu Zhe Tun, Yuan Jie, Huang Xiongwei, et al. Research progress of plant anticancer drug paclitaxel. Modern Chinese medicine research and practice, 2006, 20 (3): 58-61.

15. Wang Daming, Zhou Yun, Li Lianfang. The development trend of paclitaxel and the resources of Taxus in Yunnan Province.

16. Western Forestry Science, 2005,34 (2): 38-42.

17. Li Quan, Song Xiaomei. Taxus in the latest research progress. Modern Chinese medicine, 2008,28 (1): 66-67.

18. Qiao Yi, Zheng Chunyu. Endangered species: Taxus cuspidata. Jilin Agricultural, 20083,1: 34-5.

19. Zhang Xiuping. Development Status and Development Countermeasures of Taxus Resources. Inner Mongolia Forestry Investigation and Design, 2008,31: 57,78.

20. Zhou Zhiqiang, Liu Tong, Yuan Jilian. Study on the Characteristics of Natural Taxus chinensis Population in Muling,

21. Heilongjiang Province. Chinese Journal of Plant Ecology, 2004,28 (4): 476-482.

22. Wu Banghua, Qi Jizhong. Taxus chinensis plant geography research. Journal of Applied and Environmental Biology, 1995,1 (3): 219-225.

23. Wang Yongyi. Studies on the chemical constituents of the leaves of Taxus cuspidata. Shenyang Pharmaceutical University,

24.

25. Li Chunbin, Tong Jingjing, Fan Shengdi. Extraction and Purification of Taxol from Taxus cuspidata and HPLC Detection. Journal of Dalian Nationalities University, 2005,7 (5): 22-25.

26. An Chunzhi. Determination of active ingredients in leaves of Taxus yunnanensis. First Military Medical University, 2006.

27. Liu Benye, Ye Hechun, Li Guofeng. Studies on the research of anti-cancer drug paclitaxel. Botanical Bulletin, 1995,12 (3):

28. -14.

29. Wani MC,Taylor HL,Wall ME. Plant antitumor agents. VI. Isolation and structure of taxol,a novel antileukemic and antitumor agent from Taxus brevifolia. Journal of American Chemical Society, 1971, 93(9): 2325-2327.

30. Chang Mingjin, Li Chunqiang, Peng Ming. Study and development of natural drug paclitaxel. Anhui Agricultural Sciences, 2006,34 (2): 257-258.

31. Hu Zhihong. Taxol pharmacology and clinical research progress. Journal of Chongqing College of Education, 2005,18 (6): 46-49.

32. Zhang Xiao, beam Mei Ying, Zhang Tao. Advances in paclitaxel. China Pharmaceutical Technology and Markets, 2006,6 (4):

33. -46.

34. Zhang Jue, Lu Jiaguo, Zhu Ju. Advances in chemical research of antitumor drugs paclitaxel. Chinese Journal of New Drugs, 2006,15 (3): 178-181.

35. Yuan Jinhui, Guo Lixia, Wang Xingwang, et al. The latest research progress of paclitaxel. Chinese Journal of Pharmacology,

36. ,17 (2): 135-139.

37. Shi Q, Wang HK, Bastow KF, et al. Antitumor agents 210. Synthesis and evaluation of taxoid-epipodophyllotoxin conjugates as novel cytotoxic agents. Bioorganic u0026 Medicinal Chemistry, 2001, 9 (11): 2999-3004.

38. Dai Huifang, Mei Zhong, Xu Mei et al. Separation of paclitaxel, cephalomannine and 7-epi-10-deacetylpaclitaxel and transformation of 7-paclitaxel. Chinese Journal of Medicinal Chemistry, 2003,13 5): 288-290.

39. Xu Xuezhe. Study on extraction and separation of paclitaxel. Journal of Yanbian University (Natural Science Edition), 1998,24

40. (1): 42.

41. Erik L. M. van Rozendaal, Lelyveld GP, Beek TAv. Screening of the needles of different yew species and cultivars for paclitaxel and related taxoids. Phytochemistry, 2000, 53 (3): 383-389.

42. Su Y, Wang T, Li XY. Taxol content analysis of different tissues of Taxus mairei. Natural Product Research and Development,

43. , 13 (2): 19-20.

44. Zheng Deyong. Comparison of Taxol Content in Three Taxus Species in China. Journal of Fujian Forestry College, 2003,23 (2): 160-163.

45. Zhang Hong, Yang Minghui. Factors affecting paclitaxel in yew bark. Chinese herbal medicine, 2002, 33 (1): 39-41.

46. Zhang Fengmei. Preparation of paclitaxel in leaves of different parts of wild yew and different growing seasons. Capital Medicine, 2008 (9): 52- 53.

47. Neto AF, DiCosmo F. Distribution and amount of taxol in deferent shoot parts of Taxus cuspidata. Planta Medica, 1992, 58: 464-466.

48. Elsohly HN, Jr. EMC, Kopycki WJ, et al. Concentrations of taxol and related taxanes in the needles of different Taxus cultivars.

49. Phytochemical Analysis, 1995, 6 (3): 149-156.

50. XUE Yan-hua, ZU Yuan-gang, SHI Quan, et al. Comparative comparison of drying methods for extracting paclitaxel content in fresh leaves of Taxus cuspidata. Biophysics Newsletter, 2005, 41 (5): 657-658.




DOI: https://doi.org/10.24294/sf.v1i1.381

Refbacks

  • There are currently no refbacks.


Copyright (c) 2018 Sustainable Forestry



This site is licensed under a Creative Commons Attribution 4.0 International License.