“Langerhan Cell Histiocytosis –Review Of Literature”

Ashutosh Jaysing Thorat, Pawan Vilasrao Dawane

Article ID: 637
Vol 4, Issue 1, 2021

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Abstract


Background: Langerhans cell histiocytosis is a relatively rare unique disease process characterized by an abnormal proliferation of immature dendritic cells usually affecting children and young adults.

Discussion:  Histiocytosis are rare diseases of great biological variability and a wide range of clinical manifestations. The first manifestations of LCH may occur in the oral cavity may vary from a continuous gingival infection or a dental abscess to necrotizing ulcerating defects or a painful jaw swelling.The criteria  for diagnosis of LCH includes identification of the characteristic clinical features histopathological, Immunohistochemical findings. Various treatment modalities has been adopted including wide surgical excision along with radiotherapy,chemotherapy ,isolated radiotherapy and use of alkalizing agents.

Keywords- Langerhans cell histiocytosis, Histiocytosis X , Osteolysis of skull

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DOI: https://doi.org/10.24294/as.v1i2.637

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